Kids and Families

Listed below are a selection of research projects currently active within ISLHD.

Paediatrics

Accordion Content

Dalby-Payne J, Lau C, Bhurawala H, Teo S, Chay P, Chin R, Dowling T, Piper S, Vuillermin P, Standish J, Newnham T, Thomson-Bowe K, Rosser J, Martin A, Kapoor V, Costa-Pinto J, Sypek S, Mace A, McNab S, Simeonovic M, Thomas C, Camadoo L, Beggs S, Stewart P, Liu A, Kaufman J, Children’s Inpatient Research Collaboration of Australia and New Zealand (CIRCAN) Study of the Impact of the COVID-19 Pandemic on General Paediatric Admissions in Australia.
Locations: Wollongong Hospital.
External Partners: Multiple hospitals Australia-wide.

The aim of this multi-centre epidemiological observational study is to compare the burden of general paediatric inpatient admissions in tertiary and non-tertiary hospital across Australia pre and post-COVID-19 Pandemic.  Secondary aims will be to examine the change in profile of patients admitted under General Paediatric teams including demographic features, severity of illness and types of diagnoses.

 

Oei JL, Travadi J, Tracy M, Allgood C, Sotiropoulos J, Smyth J, Kunjunju A, Marjoribanks C, AIR Study: Air for Infant Resuscitation.
Locations: Wollongong Hospital.
External Partners: University of New South Wales, Royal Hospital for Women, John Hunter Children's Hospital, Westmead Hospital, Campbelltown Hospital.

For more than 15 years, international resuscitation guidelines have recommended the use of air (21% oxygen) to initiate respiratory support of full-term infants at birth. This is to prevent oxidative stress. However, the impact of using air instead of oxygen (which had been used for >200 years) is unknown and concerning if the infant has lung problems, necessitating extra oxygen. This project will aim to recruit 5,000 infants from >40 hospitals around the world to measure oxygen saturations (SpO2) for the first 10 minutes after birth. The primary aim of the study is to see if air allows sick babies to reach recommended oxygen saturations by 5 minutes and if this impacts on death at 24 hours.

 

Kunjunju A, Uebel H, Piper S, Where to draw the line? Comparison of two jaundice guidelines and implications on readmission for phototherapy.
Locations: Wollongong Hospital.

Phototherapy is a safe and effective treatment for neonatal unconjugated hyperbilirubinemia, which involves placing the infant under a blue spectrum light, facilitating the conversion of bilirubin to soluble isomers that are then excreted in the urine. This has reduced the need for exchange transfusion, and in many centres, also enabled the treatment of infants in the community. In this study, we are aiming to compare the two jaundice algorithm and the babies will meet the treatment threshold in both chart. If the results are significant, it will help us to revise our clinical practice.

 

Reid S, Kunjunju A, Crossing the threshold: Comparing guidelines for neonatal inpatient management of jaundice.
Locations: Wollongong Hospital.

There is significant variation in clinical practice between Australian Neonatal Units in regards to the minimum serum bilirubin level requiring phototherapy. Current guidelines used in NSW are based on the more conservative NICE guidelines, whilst Queensland utilise AAP guidelines, which advocate higher treatment thresholds. This study is significant as it may provide evidence for an alteration in clinical practice, with the potential for decreasing unnecessary medical interventions, and subsequently reducing hospital stays for neonates and their mothers.

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